How does Sickle Cell Affect the Circulatory System?
When you think about sickle cell you think about the circulatory system, thats because thats its main known system. The circulatory system transports the nutrients and oxygen to the cells in your body so they can stay healthy and perform cellular respiration. Without the circulatory system, your body could not function. The oxygen transported by the circulatory system is a needed "fuel" for all cells, tissues, and organs in the body. The product of cellular respiration, carbon dioxide, is picked up by the red blood cell and sent to the lungs. If the cells are sickle shaped, then the oxygen your cells need won't stick to the cell's hemoglobin and carbon dioxide will stay in your blood stream. If this happens, the body is seriously hindered and will eventually die!
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http://sicklecellsdisease.weebly.com/the-circulatory-system.html